Yes. Did you read the disclaimer?

Disclaimer: WINE means 'Wine Is Not an Emulator", so the statement about four layers of emulation is really a lie. To make things worse, the ZX Spectrum emulator for C64 only emulates Basic, not machine code. But that’s ok, because it all looks the same and the whole exercise is pointless anyway.

There are of course Atari and Apple emulators, but there are no emulators for those systems, so from that perspective they would be a dead end. I tried adding one level (C64 emulator for Amiga), but don’t know how to emulate HDD on Amiga.