I’m under the impression that Google deliberately hinders their YouTube platform just because you have ad-blockers. With videos taking time to buffer, seems to signal this, because it almost makes up nearly the amount of time for when ads take if you had to watch them. So since you’re ad-blocking and they don’t like that, they’ll make your experience miserable until you want to pay their service or not use ad-block.
It depends on how far away you are. Close enough to be instantly vaporized, probably not. Far enough that it just collapses the building, might do some good.
Also in places with false ceilings and hanging fixtures even light shockwaves can cause stuff to fall. Falling stuff, small fragile heads - just better to take cover than not.