We all know the pictures of the astronauts on the ISS floating around. We also suspect that a lack of gravity is bad for the body as the muscles go weak and such.
Why don’t spaceships just rotate to cause the effect of artificial gravity through centrifugal forces?
Humans have flown a total of ten manned missions that involved a Hohmann transfer: Apollo 8, Apollo 10-17, and Artemis 2. All ten flew to the Moon. On a typical Apollo mission, the outward bound coast leg is about 72 hours, between TLI and LOI, during which time they had to do the release-turn around-dock-extract maneuver with the lunar module and do at least one course correction.
We’ve been wasting tax payer dollars for more than half a century now designing and redesigning manned Mars missions that aren’t ever going to fly. Some of the various “artist’s conceptions” over the decades have included various centrifugal gravity solutions, be it the wagon wheel type or the bolas type or whatever. I don’t believe any actual hardware has even begun construction. Before you start worrying about that, you’ve got to 1. have a society healthy enough to fly manned deep space missions, and 2. figure out how to shield the crew from radiation first. Neither of which we have figured out at the moment.